Endocrine Abstracts

Introduction: Initial presentation of thyroid carcinoma can range from a solitary thyroid nodule or cervical lymphadenopathy to symptoms related to local compression. Presentation as chylothorax due to compression of thoracic duct is exceptional. The aim of this case report is to describe an extremely rare case of follicular thyroid cancer presenting as chylothorax with special attention to therapeutic aspects.Case report: A 78-years-old woman was referr...

Introduction: Hypoglycemia is the most frequent metabolic complication observed in patients with type 2 diabetes mellitus (T2DM). Moreover, rare insulinomas are the most common cause of endogenous hyperinsulinemic hypoglycemia in adults. The coincidence of insulinoma in a patient with pre-existing T2DM is an extremely rare condition and there are few case reports in the medical literature.Case report: A 76-year-old woman diagnosed with T2DM 6 years ago, ...

Introduction: The association of systemic lupus erythematosus (SLE) and dysthyroidism has been reported by several studies in a wide range of variability but studies focused on the influence of hypothyroidism on classic manifestations of SLE are scarce. Our purpose was to evaluate the prevalence of thyroid diseases in a cohort of SLE patients and the relevance of hypothyroidism with clinical and analytical parameters related to lupus.Methods/design: One ...

Introduction: Vitamin D insufficiency (D-INSUFF) has been associated with impaired immune response in human inmunodeficiency virus (HIV) patients and a worse prognosis in patients with liver fibrosis. Nevertheless, few studies have explored the influence of D-INSUFF in immunological response and liver parameters in HIV and hepatitis C virus co-infected patients (HIV/HCV) on long term highly active antiretroviral therapy (HAART) with successful immune and virological response. ...

Introduction: Pheochromocytoma multisystem crisis (PMC) is the most fulminant clinical expression of pheochromocytoma. The appropriate timing and judgment for the start of surgery and the adequate preoperative medical treatment are unclear. We report a case of PMC successfully treated with elective adrenalectomy after doxazosin blockade. The importance of an early biochemical diagnosis is discussed.Case report: A 47-year-old healthy man consulted for sud...

Introduction: Although the importance of disorders in glucose metabolism is well recognized in human immunodeficiency virus (HIV) infected patients; the clinical relevance of prediabetes in this population has been little studied. The aims of this observational study were to determine the prevalence of prediabetes in a cohort of HIV-infected patients on long term highly active antiretroviral therapy (HAART) and to assess whether this condition involves the appearance of partic...

Introduction: Vitamin D deficiency is common among people living with HIV worldwide. There is a lack of studies focusing on prevalence and consequences of low levels of vitamin D in our health care area (south of Spain). The main aim of this study is to know the status of vitamin D and its consequences on parameters related to calcium metabolism in a cohort of patients with HIV infection in our area.Methods/Design: Cross-sectional study encompassing HIV-...

Introduction: Several studies have shown that BMI and visceral adiposity index (VAI) are inversely related to serum 25-hydroxy vitamin D (25OHD) in general population. There is a lack of studies performed in HIV population, whose body fat distribution is altered by lipodystrophy or liver disease. We aimed to analyze the cross-sectional associations of VAI and BMI with the 25OHD concentration and parameters related to calcium-phosphorus metabolism in HIV-infected patients.<...

Introduction: In our setting, it is quite common that control of major risk factors of patients with type 2 diabetes (T2D) after myocardial infarction (MI) is not made by specific risk factors units (SRFU). Here, we conducted a preliminary study to investigate the effects of a SRFU intervention on metabolic and cardiovascular outcomes in T2D patients who suffered from MI.Methods/design: This retrospective and observational study was performed in one sing...

Rationale: Secondary prevention of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM) has shown benefit but the level of control is still disappointing. Most of the results are documented within clinical trials. There isn’t enough information in routine clinical practice at short-term tracing. The main aim of this study is to collect information about the level of control of major risk factors in non-selected patients.Met...